The enemies wielding this weapon can do massive damage in a matter of seconds. Also when attacked, the player will get a shaking screen with blood sprites and will be harder to aim. Enemies do not seem to reload when wielding the M60.
Due to the nature of its caliber, the M60 does more damage than the M249, but has higher recoil.
To control the weapon, fire in 2 or 3 round bursts, which is easy due to the slow rate of fire of M60.
The M60's bullets are not shared with other weapons using the same ammo.
While the M60 is fairly common among the Terrorists, some Counter-Terrorist operatives can be seen wielding this weapon. One notable mission is Recoil (mission).
"Boss" type Terrorists often prefer this weapon. However, two notable exceptions is the sniper in Hankagai mission, who uses an AWP during the mission and an MP5 at the end. Another boss in the Rise Hard mission will always be armed with a machete.
Unlike the M249, NPCs will fire this weapon from the shoulder rather than the hip, despite the fact that the M60 is heavier.
Originally, the M60 cut from Counter-Strike was supposed to cost $5000 and could become more accurate as the player continues firing.
AI M60 users never perform melee attacks unlike when wielding other weapons, even if the player enables "god" mode and reaches close proximity.